Cortex Pharmaceuticals, Inc. (NYSE Alternext US (COR)) reported that top-line data from its second Phase IIa study in opioid-induced respiratory depression (RD) demonstrated that a single oral dose of 1500mg of the AMPAKINE® compound CX717 achieved statistical significance (p = 0.005) over placebo on the primary endpoint measure of spontaneous basal respiration without affecting opioid-induced analgesia. This placebo-controlled, double-blind, randomized (more…)
America’s financial crises is fueling chronic stress and limiting some people’s ability to think clearly, control emotions and regulate bodily functions in a healthy manner. University of Alabama at Birmingham (UAB) Associate Professor Josh Klapow, Ph.D., says now is the time to take control of emotions (more…)
The news about antidepressant medications over the past several years has been mixed. The bad news from large multicenter studies such as STAR*D is that current antidepressant medications are effective, but not as effective as one might hope. Thus, there is a significant need for new treatment mechanisms for depression. On that front, there has been mixed news as well. One of the most exciting new drugs (more…)
The American College of Physicians is publishing a new guideline for the treatment of depression in Annals of Internal Medicine. ACP found no substantial differences in efficacy or quality of life among "second-generation" antidepressants used to treat depressive (more…)
There are few studies comparing the efficacy of short-term psychodynamic psychotherapy (STPP) and pharmacotherapy in major depressive disorder. A group of finnish investigators conducted a comparative study on the efficacy of STPP versus fluoxetine treatment in patients with major depressive disorder in a primary care setting.
Fifty-one (more…)
Prozac is regularly prescribed to ease the emotional pain of patients who are being treated for cancer. Buy lasix without prescription But can this common anti-depressant help to fight cancer itself?
Dr. Dan Peer of the Department of Cell Research and Immunology at Tel Aviv University is proving that it can. A study he and his colleagues recently (more…)
Thirty seven medical experts in psychiatry from across the
world have called on the medical community to take urgent action to optimize
services for people with a diagnosis of severe mental illness such as
schizophrenia or bipolar disorder(i).
Professor W. Wolfgang Fleischhacker, principal author of
Comorbid Somatic Illnesses in Patients with Severe Mental Disorders:
Clinical, Policy, and Research Challenges which was published in the Journal
of Clinical (more…)
A new study shows that antidepressant drugs which only affect serotonin, often used as first choice treatments, may not be best for depression in people with Parkinson’s disease. The new research is published in the December 17, 2008, (more…)
Researchers in the Laboratory of Structural Sciences at Van Andel Institute (VAI) have determined how the hormone corticotrophin releasing factor (CRF) precisely binds to its receptor. Buy soma pills This detailed structural information can help drug developers design new drugs for anxiety, depression, and related disorders.
"There are a few drugs in (more…)
Research published by the National Institute for Health Research Health Technology Assessment (NIHR HTA) programme has added to the evidence base on treatment for adolescents who are clinically depressed. The researchers found that for adolescents with moderate to severe major depression, the addition (more…)
Irritations of the bowel can have genetic causes. Researchers at the Institute of Human Genetics at Heidelberg University Hospital have discovered this correlation. The causes of what is known as irritable bowel syndrome (IBS), one of the most common disorders of the gastrointestinal tract, are considered unclear - making diagnosis and treatment extremely difficult. The results from Heidelberg, which were published in the prestigious (more…)
Postpartum depression (PPD) can lead to poor sleep quality, recent research shows. A study published in the current issue of the Journal of Obstetric, Gynecologic, & Neonatal Nursing shows that depression symptoms (more…)
Can scientists predict who will develop anxiety disorders years in advance? UCLA psychology professor Michelle Craske thinks so. She is four years into an eight-year study evaluating 650 students, who were 16 when the study began, to identify risk factors for the development of anxiety and depression - the most comprehensive study (more…)
A new study from the National Institutes of Health finds that massage therapy may have immediate benefits on pain and mood among patients with advanced cancer. The study appears in the September 16, 2008 issue of Annals of Internal Medicine.
In a randomized (more…)
A comprehensive review of current scientific literature, published in the peer-reviewed journal ecancer, has suggested that antidepressants can help the human body fight cancer by boosting its own immune response, amongst other mechanisms.
Not only this but they can help with side (more…)
In combination with medication, family-focused therapy appears to help
curb depression symptoms in teens with bipolar disorder, according to a
report released on September 1, 2008 in the Archives
of General Psychiatry, one of the JAMA/Archives
journals.
Bipolar disorders are characterized by occasional periods of elevated
mood, known as mania. A large portion of patients who are diagnosed
with (more…)
The teenage years are a time of emotional highs and lows. So how do you distinguish normal teenage mood swings and rebellion from actual depression? The September 2008 issue of the Harvard Mental Health Letter highlights some ways to tell.
Although depression (more…)
Depression and heart disease are the two leading disorders with the strongest contributions to the global burden of disease. Depression and heart disease are also intertwined. In recent years, much attention has been given to depression following heart attack and its effects on prognosis. Several large scale studies have been undertaken (ENRICHD, SADHART, MIND-IT, CREATE) in which depression was targeted. Although we hoped that treating (more…)
Depression is common among individuals on dialysis for kidney disease, but behavioral therapy can significantly improve their quality of life, according to a paper presented at the American Society of Nephrology’s 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania.
Many patients with kidney disease must sit through hemodialysis - the process of removing blood, purifying it, and returning (more…)
Bright white light therapy has been used to treat seasonal affective disorder (SAD) for more than 20 years. Although it remains a mainstay of treatment, in the past few years researchers have investigated ways to improve and refine light therapy, reports the November 2008 issue of the Harvard Mental Health Letter.
Improvements are necessary for three reasons. First, light therapy doesn’t work for everyone. Buy (more…)
The US Food and Drug Administration (FDA) gave the green light earlier this month for a new non-invasive treatment for depression that relies on a
magnetic device to stimulate the brain by sending magnetic pulses through the skull.
Intended for patients whose depression is not responding to anti-depressants, the new therapy, called transcranial magnetic stimulation or TMS, is said to (more…)
Danes are willing to pay more for genetic testing when treating depression than the cost of the testing itself, implying that genetic testing is socially useful.
Based on a survey among Danes the study estimates the supposed willingness-to-pay for genetic testing as part of the treatment of depression.
Pharmacogenetic testing conducted with a simple test with life-time valid results provides information (more…)
Though effective treatments are available for individuals suffering from chronic depression and anxiety, very little is known about how often these treatments are used or how prevalent these conditions are among the nation’s general population.
But in a first-of-its-kind study, UCLA researchers have developed estimates for both the prevalence of chronic psychiatric illness in the general population and (more…)
Policing is dangerous work, and the danger lurks not on the streets alone.
The pressures of law enforcement put officers at risk for high blood pressure, insomnia, increased levels of destructive stress hormones, heart problems, post-traumatic stress disorder (PTSD) and suicide, University at Buffalo researchers have found through a decade of studies of police officers.
UB researchers now are carrying out one of (more…)
Buy viagra pills Depression is common among teenage and young adult orphans in Rwanda who head households and provide care for younger children, according to a survey conducted by researchers at Tulane University that was published last month in the Archives of Pediatrics and Adolescent (more…)